Renal function tests include urinary beta2-microglobulin determination, urinary sodium and sodium excretion fraction determination, blood, urine infiltration determination, free water clearance determination and renal tubular acidosis test. Which is more important, is the diagnosis of kidney disease is based on glomerular filtration function test, urea nitrogen, serum creatinine and uric acid. Here we have a few highlights about this.
A glomerular filtration rate (GFR)
What is the glomerular filtration rate it, glomerular filtration rate what is the point? In fact, glomerular filtration rate is an important indicator of glomerular filtration function. For glomerular filtration rate can not be directly measured, must rely on a substance, by measuring a substance clearance rate to indirectly reflect the glomerular filtration rate. Such as decreased glomerular filtration rate is that kidney cells have been damaged, resulting in renal cells that glomerular filtration rate decreased.
What is serum urea nitrogen? What is the effect of serum urea on renal function? In fact, urea nitrogen is the final product of protein metabolism, the body of urea nitrogen is mainly excreted through the kidneys, a small part can be excreted through the sweat. And only when the glomerular filtration rate decreased to the original 1/2, the urea nitrogen will rise, so the determination of urea nitrogen is not very sensitive to reflect the glomerular filtration rate index.
Detection of urea nitrogen will also be affected by diet, infection, high fever and so on. However, because plasma nitrogen concentration of chronic kidney disease in the course of disease, observation and prognosis of the disease is very important, so the determination of plasma urea nitrogen is still one of the major biochemical examination of kidney disease.
Third, serum creatinine (Cr)
Serum creatinine is muscle metabolism to produce creatinine into the blood, become serum creatinine. When the glomerular filtration rate decreased to the original 1/3, the serum creatinine will rise. General serum creatinine rise common in chronic renal insufficiency, renal failure, uremia and other serious kidney disease.
Four, uric acid (UA)
Uric acid is the final product of purine metabolism, the human body has one third of uric acid from food, two-thirds by their own, excreted mostly through the kidneys. Uric acid determination of early diagnosis of renal disease, when uric acid was significantly increased, common in acute and chronic nephritis; other advanced kidney disease such as kidney tuberculosis, pyelonephritis, hydronephrosis, also seen uric acid concentration increased.
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