Although many renal function tests, but each one with our bodies are closely related. Therefore, we can not arbitrarily abandon or just select a few of them to check. Select a number of renal function tests, a comprehensive analysis to arrive at the correct test results. So, what are the methods of renal function tests?

1, endogenous creatinine clearance rate check

Low-protein diets were taken for 3 days prior to and during the test. Meat was fasted and vigorous exercise was avoided. Test light at 8 pm light, and then after 8 am the next morning to 8 hours of urine revenue will join the toluene preservative clean containers. On the test day, 2 ~ 3ml venous blood was drawn. The blood and urine at the same time for inspection. Normal values ​​ranged from 109 to 148 liters per 24 hours (or 80 to 120 milliliters per minute) with an average of 128 liters per 24 hours (or 100 milliliters per minute). Clearance rate of less than 80% of normal, suggesting that glomerular filtration dysfunction. Clearance was 70 to 51 ml / min, mildly reduced, at 50 to 31 ml / min for moderate reduction, and less than 30 ml / min for severe reduction. The clearance rate was 20 to 11 ml / min for early renal insufficiency, and 10 to 6 ml / min for advanced renal insufficiency, and less than 5 ml / min for end stage renal insufficiency.

2, blood urea nitrogen and serum creatinine determination

Take 1 ml of blood, into the anticoagulant tube, and mix well. Normal blood urea nitrogen 9 to 20 mg / liter, serum creatinine 1 to 2 mg / liter. A variety of serious renal disease caused by renal insufficiency when the whole increase. Upper gastrointestinal bleeding, severe infection and excessive protein in the diet, can make blood urea nitrogen temporarily increased. Serum creatinine concentration and other factors affected by the diet is relatively small, significantly increased, suggesting poor prognosis.

3. Phenol red (PSP) excretion test


Before the test can not use aspirin, penicillin and other drugs. Avoid diuretic drinks such as tea and coffee before and during the test. 20 minutes before the trial Zhu Huanzhe go to urination, and then drinking 300 to 400 ml, no longer drinking water. A 1 ml syringe was used to accurately extract 1 ml of 0.6% phenol red solution by intravenous injection. After the injection of 15,30,60,120 minutes to collect urine once, were collected in the clean specimen bottles, and timely delivery inspection. The excretion rate was equal to or equal to 25% at 15 min after the normal injection and greater than 55% at 120 min. Such as less than normal, said renal dysfunction, renal blood flow changes can cause diseases such as heart failure, severe hypertension and pyelonephritis, but also to reduce the phenol red excretion rate.

4, urine concentration and dilution function test

In the experiment, the patients were given a diet. Day and night within 24 hours of urination once every three hours, were collected in a clean specimen bottle. Normal daytime urine output and night urine ratio of 3 to 4: 1; 12-hour night urine output of not more than 750 ml; the highest proportion of urine above 1.020. The difference between the highest proportion of not less than 0.009. The highest proportion of less than 1.08, said renal insufficiency; the proportion of the specimen is very small, most of the urine specific gravity fixed at 1.010 or so, that the renal concentration of function Severe obstruction; day urine than the fixed at 1.019 or higher, mostly dehydrated patients.