Glucocorticoid

Glucocorticoid (Glucocorticoid), also known as "adrenal cortex hormones", is a class of steroid hormones secreted by the adrenal cortex, can also be synthesized by chemical methods. Because it can be used for general antibiotics or anti-inflammatory drugs are less than the disease, such as SARS, sepsis, etc., with regulation of sugar, fat, and protein biosynthesis and metabolism, but also has anti-inflammatory effect, called "glucocorticoid" Because it is the first to regulate the activity of carbohydrate metabolism for people to know.

The basic structural features of glucocorticoids include C3 carbonyl, Δ4 and 17β ketone side chains of adrenocorticosteroids and 17α-OH and 11β-OH unique to glucocorticoids.


The current concept of glucocorticoid not only includes the above characteristics and activity of endogenous substances, but also includes a lot of structural optimization with a similar structure and activity of synthetic drugs, the current glucocorticoid drugs are more clinical use of a class drug