2017年1月18日星期三

treatment


No special treatment of the disease, clinical manifestations and course of the disease, according to different patients with different measures, the purpose is to protect the renal function, slow disease progression.According to the clinical classification treatment of IgA nephropathy is as follows:
1. The isolation type microscopic haematuria
No special treatment, follow-up on a regular basis.
2. Type recurrent gross hematuria
Lesions such as tonsil excision, can be used according to the amount of proteinuria triple therapy (tripterygium wilfordii glycosides, emodin, ACEI/ARB).
3. Type abnormal urine test
More than triple therapy (tripterygium wilfordii glycosides, emodin, ACEI/ARB).
4. Type vasculitis
(1) the MMF treatment: a prednisolone intravenous drip shock therapy, three days after to prednisone 0.6 mg/kg. (d), every 2 weeks to reduce 5 mg to 10 mg/d/d, after maintaining the dose.MMF with 0.5 g, 2 / d start, on the basis of blood drug concentration increased to 1.5 ~ 2.0 g/d, 6 months of continuous use, by 0.75 ~ 1 g daily dose to maintain, the total course of 2 years.
(2) cyclophosphamide (CTX) therapy: a prednisolone treatment with MMF.CTX shock therapy, 1 times a month, a total of 6 months, after every 3 months 1 time.Total dose < 8 g.After the CTX treatment with azathioprine, total course of 2 years.
5. A lot of proteinuria tiny lesions (merger)
Prednisone treatment.
6. A lot of proteinuria
Low protein diet, using tripterygium wilfordii glycosides, emodin, ACEI/ARB drugs.
7. High blood pressure type
Choose to use ACEI/ARB, CCB, diuretic kinds of antihypertensive agents, proteinuria > 1.5 g / 24 cases can share tripterygium wilfordii glycosides.

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