Signs and symptoms

Signs and symptoms

The most common symptoms (40-50% of patients) will show the paroxysmal blood in the urine, usually in the nonspecific will appear after the upper respiratory tract infection, while streptococcal glomerulonephritis weeks after primary infection often appear blood in the urine;A small number of cases of gastrointestinal infection or urinary tract infections can also be referred to as the inducing factors.All these inflammatory activation mucosa reaction, to produce IgA antibodies.Low back pain sometimes happen.Blood in the urine is usually disappear in a few days later, but invisible blood in the urine may continue for a long time.The paroxysmal attack usually once every few months, most patients symptoms of blood in the urine can eventually blanking.Renal function is usually normal, rare cases, acute renal failure will happen.
20-30% of the patients, usually older patients, there will be a hidden hematuria and proteinuria (less than 2 g) every day.These patients may be no symptoms at all, are only found when doctors do urine test.So, in many cases, the disease is in the process of the mandatory medical diagnosis, such as the Japanese students are mandatory to do urine test.Even more rare will appear the following symptoms (5% each) :
Nephrotic syndrome (3-3.5 g proteinuria, diagnostic difficulties), acute renal failure (either chronic glomerular nephritis hematuria complications either acute), chronic renal failure (kidney failure in patients may have anemia, hypertension, and other symptoms, has a long-term contact hematuria and proteinuria).
A large number of systemic diseases and IgA nephropathy is concerned, such as liver failure, celiac disease, arthritis, Reiter's syndrome, mandatory spondylitis and HIV.The diagnosis of IgA nephropathy and explore for the primary disease reveals the causal relationship between them.