Signs and symptoms

Signs and symptoms

Insidious onset of the diabetic nephropathy, slow progress, early symptoms related to the kidney.Early nephropathy enlarged kidneys, glomerular filtration function and trace albuminuria sustainable for many years, also not easy to be noticed, so most of the patients with diabetic nephropathy is when a significant proteinuria or significant edema were noticed.The main clinical symptoms of the disease are as follows:
1. Proteinuria is the first clinical manifestations of diabetic nephropathy, discontinuity at first, after to sustainability.It with free method, determination of albumin in urine or micro albumin can early diagnosis of proteinuria, beneficial to control the disease.

2. Edema diabetic nephropathy edema occurs due to a large amount of proteinuria, this stage show that has developed to the late diabetic nephropathy.More associated with the clinical manifestations of GFR decline in kidney function decline, with poor outcome.

3. High blood pressure in later.To the higher stage of diabetic nephropathy in blood pressure, may be related to changes in the structure and function of diabetic renal vascular resistance have close relationship, in addition, water sodium retention is one of the factors of high blood pressure.The development of high blood pressure can worsen kidney disease and the deterioration of renal function, so the control of hypertension is very important.

4. Anemia have obvious nitrogen qualitative hematic disease in patients with diabetic nephropathy, can have mild to moderate anemia.Anemia of erythropoiesis obstacle, treatment with iron is invalid.

5. Abnormal renal function from the emergence of proteinuria to kidney dysfunction, interval time has changed a lot, if diabetes to obtain the very good control, but years of proteinuria without abnormal renal function.If the control is not good, can appear the nitrogen qualitative hematic disease, renal insufficiency.In addition, diabetic kidney disease is often associated with diabetic retinopathy.