Main symptoms of nephrotic syndrome

Main symptoms of nephrotic syndrome

 Main symptoms of nephrotic syndrome: a large amount of proteinuria, hypoalbuminemia, hyperlipidemia, hypertension
(1) proteinuria normal adult urinary protein excretion in a day not more than 150 mg. A lot of proteinuria is a result of glomerular filtration membrane caused by abnormal. Normal glomerular filtration membrane to plasma protein selective filtration function, can effectively prevent the vast majority of plasma proteins from glomerular filtration, a tiny amount of plasma proteins into the glomerular filtrate.

(2) low serum albumin leels Most of low serum albumin leels in patients with nephrotic syndrome, the serum albumin level under 30 g/L. The main reason is loss of albumin in urine, but both are not completely parallel, because the plasma albumin values is the result of a balance of albumin synthesis and catabolism.

(3) the occurrence of edema, edema and the degree of severity and hypoalbuminemia were positively correlated. However, exceptions are not uncommon.

(4) of hyperlipidemia Nephrotic syndrome characteristics of the lipid metabolism disorders for almost all kinds of lipoprotein in plasma composition is increased, the plasma total cholesterol (Ch) and low density lipoprotein cholesterol (LDL - Ch) increased significantly, triglyceride (TG) and low density lipoprotein cholesterol (VLDL - Ch).