IgA nephropathy

IgA nephropathy is the most common primary glomerular disease, refers to the glomerular mesangial area with IgA or IgA deposition mainly with or without other immunoglobulin deposition in the glomerular mesangial area Primary glomerulopathy. Types of lesions include focal segmental lesions, capillary proliferative lesions, mesangial proliferative lesions, crescentic lesions and sclerosing lesions. The clinical manifestations of recurrent nausea hematuria or microscopic hematuria, may be associated with varying degrees of proteinuria, some patients can be severe high blood pressure or renal insufficiency.

Vasculitis type
(1) MMF treatment: methylprednisolone intravenous infusion for three days, followed by prednisone 0.6mg / (kg.d), every 2 weeks to reduce 5mg / d to 10mg / d, after the maintenance of this dose. MMF to 0.5g, 2 / d began to administration, according to the plasma concentration increased to 1.5 ~ 2.0g / d, continuous use of 6 months to 0.75 ~ 1g daily dose maintenance, the total course of 2 years.
(2) cyclophosphamide (CTX) treatment: methylprednisolone with MMF treatment. CTX shock therapy, once a month for 6 months, once every 3 months. Total dose <8g. CTX treatment after the end of azathioprine maintenance, the total course of 2 years.