Nephrotic syndrome treatment

Nephrotic syndrome treatment

Delaying the progression of chronic renal insufficiency to chronic renal insufficiency includes the following measures: 1) to control blood pressure to actively control blood pressure can reduce proteinuria, can reduce glomerular hyperfiltration, slow the progress of chronic renal failure lesions. The principles of choice of antihypertensive drugs vary according to the stage of CKD, when angiotensin converting enzyme inhibitor (ACEI) or angiotensin II receptor 1 antagonist (ARB) is preferred when CCr> 30ml / min, Combined with other antihypertensive drugs. When the patient's Ccr down to 30ml / min below, the application of ACEI and ARB may cause glomerular hypoperfusion pressure leaving the glomerular filtration rate is too low, so the non-dialysis patients with CKD should be used with caution. 2) Diet Low protein diet can reduce glomerular hyperperfusion, high blood pressure and high filtration, reduce proteinuria, thus slowing down glomerular sclerosis in patients with glomerulosclerosis and interstitial fibrosis progress. When the GFR is less than 25ml / (min.l73rm ²), the amount of protein should be limited to 0.6g / (kg.d). Should ensure that sufficient calorie intake is greater than 35kcal / (kg.d), in order to maximize the use of dietary protein. In addition to the necessary amino acids or keto acid amino acid mixture. In addition, patients with high blood pressure and edema should limit salt intake. Patients with dy

slipidemia should be dietary adjustments, if necessary, should be lipid-lowering drug therapy.CRF is a slowly progressive disease, but the risk of multiple risk factors for patients with high susceptibility in the course of the disease may have deteriorated renal function. Common risk factors are: ① hypovolemia, including hypotension, dehydration, shock; ② severe infection, sepsis; ③ tissue trauma or bleeding; ④ endogenous or exogenous toxins kidney damage; ⑤ urethral obstruction; Failure to control severe hypertension and malignant hypertension. Carefully identify the cause of accelerated renal function and the reasons for the progress of targeted therapy, help to improve renal function. 2.CRF prevention and treatment of complications