Why kidney disease will be transformed into systemic lupus erythematosus

SLE (systemic lupus erythematosus, SLE) is a multisystem, multi-organ and a variety of autoantibodies appears autoimmune diseases. The disease incidence of women significantly more than men, about 10:1, the peak incidence for women of childbearing age, the elderly and children can also be sick.
SLE most often harms the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system. When patients’ kidneys are damaged,it is called Lupus Nephritis. In fact,it is a common disease in Urology Department. For more details? Leave message on below to get more details for free.
Owing to its obvious and severer symptoms and complications,it will effect patient’s normal life greatly. But how about the reasons? Why will SLE will lead to their renal damage? Why?
1. genetic factor
Based on experts,Lupus Nephritis patients who has the family history of the same disease is about 0.4% ~ 3.4%. Therefore,if one of your grandparents has Lupus Nephritis,it is OK for you to check your body timely.
2. cellular immunity
The cytotoxic antibody in patient’s serum will break T cell,reducing the T cell. On the one hand,it can reduce the the inhibition for antibody; but also will promote patients;’ disease condition. So it is necessary for patents to keep warm and avoid fat.
3. The change of humoral cell-mediated immunity immunity

The humoral immunity of DNA and anti-DNA antibody plays an important tole in effect the change of body fluid. Different Lupus Nephritis patients will have different Pathogenesis. It is necessary for patients to find their own cause of renal lesions.