Discuss the pathogenesis of hypertensive kidney disease

Discuss the pathogenesis of hypertensive kidney disease

Discuss factors of hypertensive kidney disease!Kidney is in itself a big blood, used to filter toxins in the body, and prevent protein, blood cells and other substances leaking blood vessels.High blood pressure makes the endovascular blood pressure increased, protein may be leaking, protein once leak filter system can lead to kidney damage, causing a vicious cycle.Long time the damage caused by irreversible, kidney can increase compensatory, until early failure.
There are several reasons cause of high blood pressure, kidney disease, including gender, race, such as diabetes, hyperlipidemia and high uric acid hematic disease, these factors influence each other, further aggravating the kidney damage.And hypertension incidence and severity of hypertension of renal damage and duration were positively correlated.
And renal damage in men than women are more likely to occur.The pathogenesis of primary hypertension age generally at the age of 25 to 45, and high blood pressure cause kidney damage clinical symptoms for the age of 40-60 years old.Nocturia increased, is the earliest symptoms may reflect the renal tubules have taken place in ischemic lesions, the concentration of urinary function began to decline.Then appear proteinuria, which indicates that have taken place in glomerular lesions.The degree of proteinuria is usually mild to moderate (+ or + +), 24 hours urinary protein quantitative is generally not more than 2 grams, but there are a few patients have a lot of proteinuria.Urinary sediment microscopy little red blood cells and tube type, individual patients in glomerular capillary rupture with the transient with macroscopic haematuria.Studies have confirmed that one over ten thousand will develop in patients with essential hypertension.
Can often be found that the primary hypertension caused by other organs, mainly as a complication of heart head blood-vessel, these complications may be worse than the kidney damage appears earlier, the illness is more serious, as the main or key factors affecting the prognosis.Cardiac complications is most common in hypertensive left ventricular hypertrophy, and at the same time easy to merge heart failure, coronary heart disease angina pectoris;Cerebrovascular complications of cerebral hemorrhage and cerebral infarction, cerebrovascular accident in our country in the cause of death in the first place with essential hypertension (eh).Primary hypertension can cause retinal arteriosclerosis, further cause arteriosclerosis sex retinopathy.
Retinal arteriosclerosis degree is proportional to the blood pressure, which more closely relationship with diastolic blood pressure.Retinal arteriosclerosis generally parallel to the degree of renal arteriolar sclerosis, can generally reflect the renal arteriole, so the fundus examination is very important.
Discuss factors of hypertensive kidney disease!Believe you to look at the above interpretation of the content, for high blood pressure, kidney disease have a certain understanding, hope that can explain the contents of the above to be of help.